Parkinson’s disease is a most degenerative disorder of the central nervous system. The major symptoms of parkinson’s disease result from the death of dopamine-generating cells within the locus niger of the midbrain; the explanation for this necrobiosis is unknown.
Parkinson’s disease most frequently develops once age fifty. it’s one in all the foremost common systema nervosum disorders of the aged. generally Parkinsonism happens in younger adults.In some cases, Parkinsonism runs in families. once a younker is affected, it’s actually because of a kind of the sickness that runs in families.
Nerve cells use a brain chemical referred to as monoamine neurotransmitter to assist management muscle movement. Parkinsonism happens once the nerve cells within the brain that create monoamine neurotransmitter are slowly destroyed. due deficiency of monoamine neurotransmitter, the nerve cells therein a part of the brain cannot properly send messages. This results in the loss of muscle perform. The injury gets worse with time. specifically why these brain cells waste away is unknown.
Parkinson’s is rare in youngsters. it should occur as a result of the nerves aren’t as sensitive to monoamine neurotransmitter.
The term “parkinsonism” refers to any condition that involves the categories of movement changes seen in Parkinsonism. degenerative disorder could also be caused by different disorders (called secondary parkinsonism) or side effects of some medications.
Clinical Features, Early within the course of the sickness, the foremost obvious symptoms are movement-related; these embrace shaking, rigidity, slowness of movement and issue with walking and gait.
Ayurveda Options, Kampavata is the disease condition described in ayurveda literature with similar clinical feature & one of the herbs’s active ingredient Dopamine is being used worldwide in modern system of medicines . With ayurveda approach of personalized translational medicines it can be reversed as we have observed in clinical practise at Vedanta Ayurveda.